CSS grids are amazing tools for building websites that take alot of the tedius work out of laying out pages and content on your website. On this podcast Bob talks about what CSS grid libraries are, how they work, and gives some tips on ways that you can implement them into your Drupal themes.
Links from this podcast:
960.gs
960 Creator Nathan Smith Interview
960 Drupal Theme
960 Grid Generator
Blueprint
Blueprint Drupal Theme
Blueprint Grid Generator
Block Class Module